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Submissions from 2023

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Citation: Almarwani, B.; Hamada, Y.Z.; Phambu, N.; Sunda-Meya, A. Investigating the Insertion Mechanism of Cell-Penetrating Peptide Penetratin into Cell Membranes: Implications for Targeted Drug Delivery. Biophysica 2023, 3, 620–635. https://doi.org/ 10.3390/biophysica3040042 Academic Editor: Herbert Schneckenburger Received: 14 October 2023 Revised: 4 November 2023 Accepted: 7 November 2023 Published: 11 November 2023 Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).biophysica Article Investigating the Insertion Mechanism of Cell-Penetrating Peptide Penetratin into Cell Membranes: Implications for Targeted Drug Delivery, Bashiyar Almarwani, Yahia Z. Hamada, Nsoki Phambu, and Anderson Sunda-Meya

Submissions from 2022

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Longitudinal Education and Career Outcomes of a Cancer Research Training Program for Underrepresented Students: The Meharry-Vanderbilt-Tennessee State University Cancer Partnership, Meredith L. Meadows, Sarah V. Suiter, Linda J. Sealy, Dana R. Marshall, Margaret M. Whalen, and Samuel E. Adunyah

Submissions from 2021

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High-Fat Diet-Induced Obese Effects of Adipocyte-Specific CXCR2 Conditional Knockout in the Peritoneal Tumor Microenvironment of Ovarian Cancer, Deokyeong Choe, Eun-Sook Lee, Alicia Beeghly-Fadiel, Andrew J. Wilson, Margaret M. Whalen, Samuel E. Adunyah, and Deok-Soo Son

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Manganese Oxide Carbon-Based Nanocomposite in Energy Storage Applications, Mulugeta Wayu

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Evaluation of triclosan exposures on secretion of pro-inflammatory cytokines from human immune cells, Wendy J. Wilburn, Sara Jamal, Farah Ismail, Dylan Brooks, and Margaret Whalen

Submissions from 2020

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Efficient eco-friendly syntheses of dithiocarbazates and thiosemicarbazones, Nur Halilatul Sadiqin O. Ali, Malai Haniti S. A. Hamid, Nurul Amirah 'Aqilah Mohamad' Asri Putra, Hajar Azirah Adol, Aminul Huq Mirza, Anwar Usman, Tasneem A. Siddiquee, Md. Rejaul Hoq, and Mohammad R. Karim

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Comparative Analysis of Water Quality Disparities in the United States in Relation to Heavy Metals and Biological Contaminants, Kaleh Karim, Sujata Guha, and Ryan Beni

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Dibutyltin alters immune cell production of the pro-inflammatory cytokines interleukin (IL) 1β and IL-6: role of mitogen-activated protein kinases and changes in mRNA, Linda B Sushak, Sahra Gabure, JaQuel Maise, Jessica Arnett, and Margaret Whalen

Submissions from 2019

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The organochlorine pesticides pentachlorophenol and dichlorodiphenyltrichloroethane increase secretion and production of interleukin 6 by human immune cells, Tamara J. Martin, Sahra Gabure, JaQuel Maise, Sequena Snipes, Margarita Peete, and Margaret M. Whalen

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Exposures to the Environmental Contaminants Pentachlorophenol (PCP) and Dichlorodiphenyltrichloroethane (DDT) Increase Production of the Pro-inflammatory cytokine, Interleukin 1-Βeta (IL-1β), in Human Immune Cells, Tamara J. Martin, JaQuel Maise, Sahra Gabure, and Margaret M. Whalen

Submissions from 2018

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Vesicles mimicking normal and cancer cell membranes exhibit differential responses to the cell-penetrating peptide Pep-1, Bashiyar Almarwani, Esther Nzuzi Phambu, Christopher Alexander, Ha Aimee T. Nguyen, Nsoki Phambu, and Anderson Sunda-Meya

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Synthesis of interleukin 1 beta and interleukin 6 in human lymphocytes is stimulated by tributyltin, Shyretha Brown, Mariam Boules, Nafisa Hamza, Xiaofei Wang, and Margaret Whalen

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CXCR2 is a negative regulator of p21 in p53-dependent and independent manner via Akt-mediated Mdm2 in ovarian cancer, Rosa Mistica C. Ignacio, Yuan-Lin Dong, Syeda M. Kabir, Hyeongjwa Choi, Eun-Sook Lee, Alicia Beeghly-Fadiel, Margaret M. Whalen, and Deok-Soo Son

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Chemokine Network and Overall Survival in TP53 Wild-Type and Mutant Ovarian Cancer, Rosa Mistica C. Ignacio, Eun-Sook Lee, Andrew J. Wilson, Alicia Beeghly-Fadiel, Margaret M. Whalen, and Deok-Soo Son

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Obesity-Induced Peritoneal Dissemination of Ovarian Cancer and Dominant Recruitment of Macrophages in Ascites, Rosa Mistica C. Ignacio, Eun-Sook Lee, Andrew J. Wilson, Alicia Beeghly-Fadiel, Margaret M. Whalen, and Deok-Soo Son

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Tributyltin stimulates synthesis of interferon gamma and tumor necrosis factor alpha in human lymphocytes, Shanieek Lawrence, Farah Ismail, Sarah Z. Jamal, and Margaret M. Whalen

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Investigation on the reactivity of tetranuclear Group 7/8 mixed-metal clusters toward triphenylphosphine, Md. Rassel Moni, Md. Jadu Mia, Shishir Ghosh, Derek A. Tocher, Shaikh M. Mobin, Tasneem A. Siddiquee, and Shariff E. Kabir

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Polysaccharide-mediated synthesis of melanins from serotonin and other 5-hydroxy indoles, Koen Vercruysse, Astiney Clark, Noor Alattas, Dylan Brooks, Nafisa Hamza, and Margaret Whalen

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Flame retardants, hexabromocyclododecane (HCBD) and tetrabromobisphenol a (TBBPA), alter secretion of tumor necrosis factor alpha (TNFα) from human immune cells, Sharia Yasmin and Margaret Whalen

Submissions from 2017

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Butyltin compounds alter secretion of interleukin 6 from human immune cells, Shyretha Brown, Wendy Wilburn, Tyesha Martin, and Margaret Whalen

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Novel trifluoromethylated 9-amino-3,4-dihydroacridin-1(2H)-ones act as covalent poisons of human topoisomerase IIα, Lorena Infante Lara, Alexis Sledge, Amine Laradji, Cosmas O. Okoro, and Neil Osheroff

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Genome Structure of Bacillus cereus tsu1 and Genes Involved in Cellulose Degradation and Poly-3-Hydroxybutyrate Synthesis, Hui Li, Suping Zhou, Terrance Johnson, Koen Vercruysse, Lizhi Ouyang, Ranganathan Parthasarathy, Nsoki Phambu, Alexander J. Ropelewski, and Theodore W. Thannhauser

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Effects of pentachlorophenol and dichlorodiphenyltrichloroethane on secretion of interferon gamma (IFNγ) and tumor necrosis factor alpha (TNFα) from human immune cells, Reda Massawe, Leon Drabo, and Margaret Whalen

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Chain length effect on the structure and stability of antimicrobial peptides of the (RW)n series, Nsoki Phambu, Bashiyar Almarwani, Arlette M. Garcia, Nafisa S. Hamza, Amira Muhsen, Jacqueline E. Baidoo, and Anderson Sunda-Meya

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Identification of hydrated and dehydrated lipids and protein secondary structures in seeds of cotton (Gossypium hirsutum) line, Diwas Kumar Silwal, Nsoki Phambu, Bharat Pokharel, and Ahmad Naseer Aziz

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Gum Arabic promotes oxidation and ester hydrolysis, Koen P. Vercruysse, Lauren E. Tyler, and Jade Readus

Submissions from 2016

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High salt induces anti-inflammatory MΦ2-like phenotype in peripheral macrophages, Suneetha Amara, Margaret M. Whalen, and Venkataswarup Tiriveedhi

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Oleanolic Acid Inhibits High Salt-Induced Exaggeration of Warburg-like Metabolism in Breast Cancer Cells, Suneetha Amara, Mu Zheng, and Venkataswarup Tiriveedhi

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Dibutyltin-induced alterations of interleukin 1beta secretion from human immune cells, Shyretha Brown, Shahin Tehrani, and Margaret M. Whalen

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Tributyltin exposure alters cytokine levels in mouse serum, Shanieek Lawrence, Samuel T. Pellom Jr., Anil Shanker, and Margaret M. Whalen

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Exposures to the environmental toxicants pentachlorophenol (PCP) and dichlorodiphenyltrichloroethane (DDT) modify secretion of interleukin 1-beta (IL-1β) from human immune cells, Tamara J. Martin and Margaret M. Whalen

Submissions from 2015

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Hexabromocyclododecane and tetrabromobisphenol A alter secretion of interferon gamma (IFN-γ) from human immune cells, Haifa Almughamsi and Margaret M. Whalen

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Synthesis of β-triphosphotriester pronucleotides, Yousef Beni, Chandravanu Dash, and Keykavous Parang

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Effect of quercetin, genistein and kaempferol on glutathione and glutathione-redox cycle enzymes in 3T3-L1 preadipocytes, William Y. Boadi, Paul K. Amartey, and Andrew Lo

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Violacein induces p44/42 mitogen-activated protein kinase‑mediated solid tumor cell death and inhibits tumor cell migration, Toral Mehta, Koen P. Vercruysse, Terrance Johnson, Anthony Okechukwu Ejiofor, Elbert Myles, and Quincy A. Quick

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Activation of protein kinase C and protein kinase D in human natural killer cells: effects of tributyltin, dibutyltin, and tetrabromobisphenol A, Krupa Rana and Margaret Whalen

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Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules, Charles T. Spencer, Jelena S. Bezbradica, Mireya G. Ramos, Chenoa D. Arico, Stephanie B. Conant, Pavlo Gilchuk, Jennifer J. Gray, Mu Zheng, Xinnan Niu, William Hildebrand, Andrew J. Link, and Sebastian Joyce

Submissions from 2014

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Catalyst free, base free microwave irradiated synthesis of aryl nitrites from potassium aryltrifluoroborates and bismuth nitrate, Mohammad Al-Masum and Rebecca L. Welch

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Octyl (2E)-2-[2-(di­phenyl­phosphan­yl)benzyl­idene]hydrazinecarbodi­thio­ate, Izuddin Asri, Malai Haniti S. A. Hamid, Aminul Huq Mirza, Mohammad Akbar Ali, and Mohammad Rezaul Karim

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Tributyltin alters secretion of interleukin 1 beta from human immune cells, Shyretha Brown and Margaret Whalen

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Coordination Nature of 4-Mercaptoaniline to Sn(II) Ion: Formation of a One Dimensional Coordination Polymer and Its Decomposition to a Mono Nuclear Sn(IV) Complex, Eon S. Burkett and Tasneem A. Siddiquee

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Brominated flame retardants, tetrabromobisphenol A and hexabromocyclododecane, activate mitogen-activated protein kinases (MAPKs) in human natural killer cells, Anita Cato, Lindsay Celada, Esther Caroline Kibakaya, Nadia Simmons, and Margaret M. Whalen

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2,9-Bis(5-sulfanylidene-4,5-di­hydro-1,3,4-oxa­diazol-2-yl)-1,10-phenanthroline dimethyl sulfoxide disolvate, Mohammad A. Rahman, Mohammad R. Karim, Md Arifuzzaman, Tasneem Siddiquee, and Lee M. Daniels

Submissions from 2013

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In vitro anticancer screening of 24 locally used Nigerian medicinal plants, Saudat Adamson Fadeyi, Olugbeminiyi O. Fadeyi, Adedeji A. Adejumo, Cosmas Okoro, and Elbert L. Myles

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Effects of butyltins on mitogen-activated-protein kinase kinase kinase and Ras activity in human natural killer cells, Lindsay J. Celada and Margaret M. Whalen

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A Novel Algorithm for Validating Peptide Identification from a Shotgun Proteomics Search Engine, Ling Jian, Xinnan Niu, Zhonghang Xia, Parimal Samir, Chiranthani Sumanasekera, Zheng Mu, Jennifer L. Jennings, Kristen L. Hoek, Tara Allos, Leigh M. Howard, Kathryn M. Edwards, P. Anthony Weil, and Andrew J. Link

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Secretion of interferon gamma from human immune cells is altered by exposure to tributyltin and dibutyltin, Shanieek Lawrence, Jacqueline Reid, and Margaret Whalen

Submissions from 2012

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A novel route to organonitrites by Pd-catalyzed cross-coupling of sodium nitrite and potassium organotrifluoroborates, Mohammad Al-Masum, Nabil Saleh, and Tasfia Islam

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Lipid peroxides and glutathione status in human progenitor mononuclear (U937) cells following exposure to low doses of nickel and copper, William Y. Boadi, Shalandus Harris, Justin B. Anderson, and Samuel E. Adunyah

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Host–Guest Complex of β-Cyclodextrin and Disulfide Form of 4-Aminothiophenol, Taylor A. Cappadona, Lee M. Daniels, and Tasneem A. Siddiquee

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Effects of DDT and triclosan on tumor-cell binding capacity and cell-surface protein expression of human natural killer cells, Tasia Hurd-Brown, Felicia Udoji, Tamara Martin, and Margaret M. Whalen

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Tributyltin and dibutyltin alter secretion of tumor necrosis factor alpha from human natural killer cells and a mixture of T cells and natural killer cells, Kelsi Hurt, Tasia Hurd-Brown, and Margaret Whalen

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Synthesis of Some New Fluorinated Hexahydroquinoline and Acridinedione Derivatives in Trifluoroethanol, Cosmas O. Okoro, Mumiye A. Ogunwale, and Tasneem Siddiquee

Submissions from 2011

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Pentachlorophenol decreases tumor-cell-binding capacity and cell-surface protein expression of human natural killer cells, Tasia Hurd, Jasmine Walker, and Margaret M. Whalen

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Tetrabromobisphenol A decreases cell-surface proteins involved in human natural killer (NK) cell–dependent target cell lysis, Tasia Hurd and Margaret M. Whalen

5,7-Dibromo-3-trifluoro­methyl-3,4-dihydro­acridin-1(2H)-one, Cosmas O. Okoro, Tasneem Siddiquee, and Olugbeminiyi O. Fadeyi

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Ziram activates mitogen-activated protein kinases and decreases cytolytic protein levels in human natural killer cells, Thyneice R. Taylor and Margaret M. Whalen

Submissions from 2010

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Role of Protein Kinase C in TBT-Induced Inhibition of Lytic Function and MAPK Activation in Human Natural Killer Cells, Abraham B. Abraha, Krupa Rana, and Margaret M. Whalen

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Activation of p44/42 in human natural killer cells decreases cell-surface protein expression: Relationship to tributyltin-induced alterations of protein expression, Fred D. Dudimah, Abraham Abraha, Xiaofei Wang, and Margaret M. Whalen

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Activation of p44/42 MAPK plays a role in the TBT-induced loss of human natural killer (NK) cell function, Fred D. Dudimah, Denisha Griffey, Xiaofei Wang, and Margaret M. Whalen

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Dibutyltin activates MAP kinases in human natural killer cells, in vitro, Sabah O. Odman-Ghazi, Abraham Abraha, Erica Taylor Isom, and Margaret M. Whalen

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Effects of butyltin exposures on MAP kinase-dependent transcription regulators in human natural killer cells, Rachel J. Person and Margaret M. Whalen

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Immunosuppressive effects of triclosan, nonylphenol, and DDT on human natural killer cells in vitro, Felicia Udoji, Tamara Martin, Rachel Etherton, and Margaret M. Whalen

Submissions from 2009

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Hexabromocyclododecane decreases the lytic function and ATP levels of human natural killer cells, Natasha C. Hinkson and Margaret M. Whalen

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Hexabromocyclododecane decreases tumor-cell-binding capacity and cell-surface protein expression of human natural killer cells, Natasha C. Hinkson and Margaret M. Whalen

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Tetrabromobisphenol A has immunosuppressive effects on human natural killer cells, Esther Caroline Kibakaya, Krishna Stephen, and Margaret M. Whalen

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Increases in Cytosolic Calcium Ion Levels in Human Natural Killer Cells in Response to Butyltin Exposure, Rhonda Lane, Sabah O. Ghazi, and Margaret M. Whalen

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Glutathione diminishes tributyltin- and dibutyltin-induced loss of lytic function in human natural killer cells, Jeralyn J. Powell, McLisa V. Davis, and Margaret M. Whalen

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Ethyl 1-acetyl-1H-indole-3-carboxyl­ate, Tasneem Siddiquee, Shahid Islam, Dennis Bennett, Matthias Zeller, and Mahmun Hossain

Submissions from 2008

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The role of p44/42 activation in tributyltin-induced inhibition of human natural killer cells: effects of MEK inhibitors, Abraham B. Abraha and Margaret M. Whalen

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Pentachlorophenol decreases ATP levels in human natural killer cells, Ugochukwu Nnodu and Margaret M. Whalen

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Effects of ziram on tumor-cell-binding capacity, cell-surface marker expression, and ATP levels of human natural killer cells, Thyneice R. Taylor and Margaret M. Whalen

Submissions from 2007

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An Ab Initio Study of the Structures, Vibrational Spectra, and Energetics of AlSHX (X = –1, 0, +1), Sujata Guha and Joseph S. Francisco

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Effects of a series of triorganotins on ATP levels in human natural killer cells, Laurin N. Holloway, Keith H. Pannell, and Margaret M. Whalen