Phthalic Anhydride, New Reagent with Organotrifluoroborates for the Direct Aroylation Reaction
Abstract
We have devised a novel approach for the synthesis of aromatic ketones via a one-step direct aroylation process. This innovative method employs aroyl chlorides and potassium organotrifluoroborates as reactants, with palladium catalysis facilitating the reaction in the presence of a microwave system. Furthermore, we have introduced phthalic anhydride as a pioneering source of aroyl moieties, enabling cross-coupling with potassium organotrifluoroborates to generate the desired products. Collectively, these breakthroughs have substantially advanced the realm of organic synthesis, paving the way for efficient and expeditious production of crucial compounds.
Subject Area
Chemistry|Organic chemistry
Recommended Citation
Grady Clopton,
"Phthalic Anhydride, New Reagent with Organotrifluoroborates for the Direct Aroylation Reaction"
(2023).
ETD Collection for Tennessee State University.
Paper AAI30418016.
https://digitalscholarship.tnstate.edu/dissertations/AAI30418016