Medicinal Plants from Saudi Arabia: In Vitro Cytotoxicity Evaluation on HeLa and PC3 Cell Lines

Mada Yousef Bahadi, Tennessee State University


Cancer is the name given to a range of specific illnesses resulting from one of our body's own cell growing out of control. There are more than 200 different types of cancer, each with different causes and symptoms requiring different treatments. The aim of any treatment is to remove cancerous cells, making sure the cancer does not return. This can be challenging; even if just one cancerous cell remains after treatment, it has the potential to create a new tumor. Natural products are well recognized as sources of drugs for several human ailments including cancer for thousands of years. Plants from Saudi Arabia, which include Allium sativum, Commiphora myrrha, Saussurea costus, Salvia officinals, Melissa officinals have been collected to be tested for cytotoxicity activity of HeLa and PC3 cell lines. In this study the results that obtained from medicinal plants screened indicate that 5 plant extracts exhibited promising cytotoxic activity against human cancer cells. Melissa Officials, Commiphora Myrrha, Salvia Officinalis and Saussurea Costus demonstrated the potential for the treatment of HeLa and PC3. The studies also revealed that Allium sativum has less effective in HeLa and no effective at all in PC3.

Subject Area

Molecular biology|Genetics|Cellular biology|Oncology

Recommended Citation

Mada Yousef Bahadi, "Medicinal Plants from Saudi Arabia: In Vitro Cytotoxicity Evaluation on HeLa and PC3 Cell Lines" (2014). ETD Collection for Tennessee State University. Paper AAI1585613.