The Anti-Carcinogenic Effect of Solanum lycopersicum on Various Cancer Cell Lines

Ashley Jennean Blair, Tennessee State University


Today cancer is the second leading cause of death worldwide. World Health Organization estimates that 80% of the world’s population relies heavily on traditional medicines for their primary health care. Recently, researchers have developed new methods for cancer treatment including various phytochemicals obtained from different plant species, which could lead to medicines that have little or no side effects. Solanum lycopersicum is a medicinal plant known as the tomato. It has been studied for its anti-inflammatory and antioxidant effects, specifically in prostate cancer and cardiovascular disease. Many studies have proven that tomato can reduce/inhibit cancer cell growth in prostate, breast, lung, colon, gastric, pancreas, and ovarian cancer. Not only does it affect cancer, but other diseases such as UV- induced sunburn, gingivitis, mental disorders, and asthma. An in vitro anti-carcinogenic protocol was used to determine the effect of three different crude extracts of Solanum lycopersicum on various human breast and prostate cancer cell lines (MCF-7, BT20, BT549, and PC3). After several experiments with three different strains of Solanum lycopersicum, the data revealed a decrease of cancer cell growth concluding inhibition of cancer cell growth. To determine why there is a reduction of viability and the repression cell growth. More research is needed to determine the mechanism/s of inhibition.

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Recommended Citation

Ashley Jennean Blair, "The Anti-Carcinogenic Effect of Solanum lycopersicum on Various Cancer Cell Lines" (2017). ETD Collection for Tennessee State University. Paper AAI10641435.