Saudi Arabia folk medicine plants (Costus, Fenugreek, Rhamuns) effect on cancer cell lines (A549, Hela, BT549, Colo320, SW620)

Abrar Hamzah Shaldoom, Tennessee State University


There are many definitions of cancer. Cancer refers to as a group of more than a hundred diseases that can originate in many different parts of the body. Many people suffer from this disease and there are over fourteen million people that have cancer around the globe. Cancer is a common disease. More than 100 types of cancer exist, and the common ones include breast, prostate, colon, cervical, lung, and skin cancers. If the cancer is left untreated, it will spread through the body and eventually lead to death. The common treatments used to treat the cancer are chemotherapy and physiotherapy. From the beginning of human history plants have been used for medical purposes. The plants are natural source and any living organism uses plants. For many years natural compounds have been effective in treating cancer. Plants have played a significant role in the development of anti-cancer compounds. More investigations are needed to provide options for the treatment of cancer. The anti-cancer compounds from plants are effective in several types of cancer cells. That anti-cancer compounds are isolated from the plant. The plants that I am investigating are Costus, Fenugreek and Rhamnus. These plants were used in this study to determine their effects on five cancer cell lines: lung cancer (A549), colon cancer (SW620) (Colo320), breast cancer (BT549), and cervical cancer (HeLa). Growth analysis was determined using a cell viability indicator Alamar blue and a florescent plate reader. These three test compounds we get them from methanolic leaf, seed and root extracts. Also, Costus, Fenugreek and Rhamnus have demonstrated potential for containing novel anti-tumor compounds.

Subject Area

Biology|Alternative Medicine

Recommended Citation

Abrar Hamzah Shaldoom, "Saudi Arabia folk medicine plants (Costus, Fenugreek, Rhamuns) effect on cancer cell lines (A549, Hela, BT549, Colo320, SW620)" (2016). ETD Collection for Tennessee State University. Paper AAI10243208.