Analyses of Anise and Ginger as Antitumor Compounds for cell line A549, HeLa and BT549

Hailah S Olaywi, Tennessee State University


Cancer is a serious disease that threatens the lives of many people. Where the cancer is not one disease, but is considered by many diseases. Cancer is an umbrella name for many related diseases that result from malignant tumors. Cancer is mainly a genetic disease, occurring due to genetic changes in cell functionality, causing them to grow and proliferate uncontrollably. The genetic changes could be hereditary, or occur due to external factors during an individual’s lifetime. There are about 100 types of cancer, which are named according to the originating tissue or organ. The development of science was the discovery of medical solutions for chemical treatment of this serious disease. Surgery is the most common treatment for cancer that could completely alleviate cancer as long as it has not metastasized. The other treatment is Radiation therapy involves the destruction of cancer cells by radiating the cancer cells with high-energy X-rays or gamma rays. Also, Chemotherapy entails the use of drugs that target the proliferating cells by damaging the DNA or proteins. In recent years, the use of plants as a kind of therapy to influence the growth of cancer is a good way, which had a marked effect. Medicinal plants have been exploited for the treatment of cancer due to their antioxidant properties and anticancer activity. The use of plants for cancer treatment is toxic-free, alleviates adverse side effects, and reduces the cost of treatment. That was to get effective results in this research, through the use of certain plants extracts (Ginger and Anise) with different concentrations ranging between 15 and 0.1 μg/μl, Against A-549 lung cancer cell line, BT-549 breast cancer cell line, and HeLa cell. It has been reached that both extracts had an active role in the inhibition of the growth of these cancer cells.

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Recommended Citation

Hailah S Olaywi, "Analyses of Anise and Ginger as Antitumor Compounds for cell line A549, HeLa and BT549" (2015). ETD Collection for Tennessee State University. Paper AAI10003947.