Growth Inhibitory Effect of Perganum, Sage, and Olive leave Plant Extracts on Breast/Lung Cancer Cell Lines

Ola Almusallam, Tennessee State University

Abstract

Cancer is a major public health problem in the United States and many other parts of the world. One in 4 deaths in the United States is due to cancer. Cancer is a class of diseases characterized by out-of-control cell growth. There are over 100 different types of cancer, and each is classified by the type of cell that is affected. Cancer occurs when there are changes in the genes responsible for cell growth. Also it can spread to one or many parts of the body. We are becoming increasingly more aware of the fact that we can make treatment from Natural product sources as Plant to attack the growing issue of cancer. Sage Leaves (Salvia Officanlis), Perganum Leaves (Harmala), and Olive Leaves (Olea europaea) were used in this study to determine their effects on two cancer cell lines, A549 and Mcf- 7. Our findings revealed that Salvia Officanlis, Perganum Harmala, and Olea Europaea have significant effect on both cell lines (MCF-7 Breast cancer cell line and A549 lung cancer cell line). Salvia Officanlis Leaf extracts have more effect on MCF-7 and A549 than Perganum Harmala and Olea Europaea, it significantly decreased the growth rate and cell survival of both cancer cell lines at all concentrations. In future, we are going to study that how Salvia Officanlis, Perganum Harmala, and Olea Europaea act with MCF-7 Breast cancer cell line and A549 lung cancer cell line to inhibit their growth.^

Subject Area

Biology, Genetics

Recommended Citation

Ola Almusallam, "Growth Inhibitory Effect of Perganum, Sage, and Olive leave Plant Extracts on Breast/Lung Cancer Cell Lines" (2014). ETD Collection for Tennessee State University. Paper AAI1585726.
http://digitalscholarship.tnstate.edu/dissertations/AAI1585726

Share

COinS