New Organic Transformation by Introducing Allyltrifluoroborates for Direct Aroylation, And Amination Reactions

Kwei-Yu Liu, Tennessee State University

Abstract

One of the most significant and widely used methods in organic synthesis is transition metal-catalyzed allylation reactions. Potassium allyltrifluoroborate and potassium crotyltrifluoroborate are new entities in organic transformation. The first part of this thesis deals with the development of direct aroylation reactions in which microwave irradiated, PdCl2(dtbpf) catalyzed, direct cross-coupling reactions of aroyl chlorides with potassium crotyl/allyltrifluoroborates (Masum-Liu Reaction) has demonstrated. Regioselectivity of the cross-coupling product is varied from crotyltrifluoroborate to allyltrifluoroborate. ^ In the second part of the thesis, a palladium-catalyzed direct amination cross- coupling reaction with allyltrifluoroborate has been established. The products are shown with material balance, which are observed from GC-MS, and regioselectivity of the products are shown as N-allylated product.^

Subject Area

Chemistry, Organic

Recommended Citation

Kwei-Yu Liu, "New Organic Transformation by Introducing Allyltrifluoroborates for Direct Aroylation, And Amination Reactions" (2011). ETD Collection for Tennessee State University. Paper AAI1502726.
http://digitalscholarship.tnstate.edu/dissertations/AAI1502726

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