The cytotoxicity effect of rosemary and myrrh extracts on cancer cell lines

Areej Mathil Alanazi, Tennessee State University

Abstract

The word ‘cancer’ can be used to describe hundreds of diseases. It is the most common disease to cause morbidity and mortality around the world. Regardless of the strides that have occurred in regard to treatment and manipulation of cancer progression, significant advancements are still necessary. For example, chemotherapy sometimes causes undesired side effects. Therefore, it might be helpful to use natural therapies to treat cancer patients as such natural compounds might reduce the adverse side effects of chemotherapy. In the present study, we determined the effects of crude methanolic extracts of Commiphora myrrha (i.e., myrrh) and Rosmarinus officinalis (i.e., rosemary) on inhibiting the growth of cancer cells. The alamarBlue Cell Viability assay protocol and fluorescent analysis were used to evaluate the cytotoxicity of the extracts. In this experiment, four types of cancer cells—lung cancer (A549), colon cancer (SW620), breast cancer (MCF7), and cervical cancer (HeLa)—were exposed to myrrh and rosemary extracts. The findings indicate that the Commiphora myrrha gum extract showed the highest anticancer activity when exposed to the SW620 colon cancer cell lines. The Rosmarinus officinalis leaf extract showed the highest anticancer activity when exposed to the A549 lung cancer cell lines.^

Subject Area

Biology|Molecular biology|Genetics

Recommended Citation

Areej Mathil Alanazi, "The cytotoxicity effect of rosemary and myrrh extracts on cancer cell lines" (2016). ETD Collection for Tennessee State University. Paper AAI10158581.
http://digitalscholarship.tnstate.edu/dissertations/AAI10158581

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